Streptococcus salivarius and Reduced Ventilator-Associated Pneumonia

Doses used in studies

mg/day: 500 (median 500, IQR 500–500) — 1 study

Time to effect

Median: 5 days · IQR 5 days–5 days · Range 5 days–5 days — Reported in 1 of 1 study

1 of 1 paper

Effect of probiotic colonization on oral hygiene and ventilator-associated pneumonia in ICU patients: a triple-blind randomized controlled trial.

2026-02-03
RCT
BMC infectious diseases 26(1)
- Ahmad Salehi
- Farzad Ebrahimzadeh
- Ali Behzadfar
- Maryam Hashemi
- Sajad Yarahmadi

PubMed: 41634618
DOI: 10.1186/s12879-026-12711-1

3 Insights on

Reduced Ventilator-Associated Pneumonia

High evidence
Clinical

The proportion of patients at moderate to high risk of developing ventilator-associated pneumonia increased in the control group from 45% to 70%, whereas it decreased in the intervention group from 60% to 50%.

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: two daily doses of 250 mg of Streptococcus salivarius probiotic solution