Streptococcus thermophilus SEBiotic and Increased KLF4 Protein Levels

• Characterization of Mucus-Related Properties of Streptococcus thermophilus: From Adhesion to Induction

  • 2018-07-24
  • Frontiers in Physiology 9
  • • N. Fernandez
    • Laura Wrzosek
    • J. M. Radziwill-Bienkowska
    • B. Ringot-Destrez
    • M. Duviau
    • Marie‐Louise Noordine
    • V. Laroute
    • V. Robert
    • C. Cherbuy
    • M. Daveran-Mingot
    • M. Cocaign-Bousquet
    • R. Léonard
    • C. Robbe-Masselot
    • F. Rul
    • E. Ogier-Denis
    • Muriel Thomas
    • M. Mercier-Bonin

  • PubMed: 30087622
  • DOI: 10.3389/fphys.2018.00980

  6 Insights on

  • Increased KLF4 Protein Levels

  • Low evidence

  The presence of *S. thermophilus* as the unique bacteria in the digestive tract of gnotobiotic rats...increased the amount of the mucus-inducer KLF4 transcription factor. Lactate significantly increased KLF4 protein levels in HT29-MTX cells.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes