Streptococcus thermophilus VPro 23 and Increased Monocarboxylic Acid Transporter mRNAs

• Impact of the Metabolic Activity of Streptococcus thermophilus on the Colon Epithelium of Gnotobiotic Rats*

  • 2011-03
  • Clinical Trial
  • Journal of Biological Chemistry 286(12)
  • • F. Rul
    • L. Ben-Yahia
    • F. Chegdani
    • Laura Wrzosek
    • Stéphane Thomas
    • Marie‐Louise Noordine
    • C. Gitton
    • C. Cherbuy
    • P. Langella
    • Muriel Thomas

  • PubMed: 21239485
  • DOI: 10.1074/jbc.M110.168666

  6 Insights on

  • Increased Monocarboxylic Acid Transporter mRNAs

  • Low evidence
  • Animal Study

  At the level of the colonic epithelium, the abundance of monocarboxylic acid transporter mRNAs (SLC16A1 and SLC5A8) and a protein involved in the cell cycle arrest (p27(kip1)) increased in the presence of S. thermophilus compared with germ-free rats.

  Effect

  Neutral

  Effect size

  Moderate