Streptococcus thermophilus Y08 AF and Enhanced Glycolysis Pathway Activation

• Impact of the Metabolic Activity of Streptococcus thermophilus on the Colon Epithelium of Gnotobiotic Rats*

  • 2011-03
  • Clinical Trial
  • Journal of Biological Chemistry 286(12)
  • • F. Rul
    • L. Ben-Yahia
    • F. Chegdani
    • Laura Wrzosek
    • Stéphane Thomas
    • Marie‐Louise Noordine
    • C. Gitton
    • C. Cherbuy
    • P. Langella
    • Muriel Thomas

  • PubMed: 21239485
  • DOI: 10.1074/jbc.M110.168666

  6 Insights on

  • Enhanced Glycolysis Pathway Activation

  • Low evidence
  • Animal Study

  Indeed, we showed that the main response of S. thermophilus in the rat's GIT was the massive induction of the glycolysis pathway, leading to formation of lactate in the cecum.

  Effect

  Neutral

  Effect size

  Moderate