Impact of Acute and Sub-Acute Gluten Exposure on Gastrointestinal Symptoms and Psychological Responses in Non-Coeliac Gluten Sensitivity: A Randomised Crossover Study.
- 2025-03-26
- RCT · n = 16
- United European gastroenterology journal 13(7)
- Julie Iven
- Annelies Geeraerts
- Tim Vanuytsel
- Jan Tack
- Lukas Van Oudenhove
- Jessica R Biesiekierski
- PubMed: 40138597
- DOI: 10.1002/ueg2.70014
- High evidence
- Clinical
Negative affect scores were higher and positive affect scores were lower in NCGS compared to HC (p = 0.01 and p = 0.04, respectively). No significant group-by-nutrient interactions were observed.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 16 g (acute); 16 g/day for 5 days (sub-acute)