Impact of Acute and Sub-Acute Gluten Exposure on Gastrointestinal Symptoms and Psychological Responses in Non-Coeliac Gluten Sensitivity: A Randomised Crossover Study.
- 2025-03-26
- RCT · n = 16
- United European gastroenterology journal 13(7)
- Julie Iven
- Annelies Geeraerts
- Tim Vanuytsel
- Jan Tack
- Lukas Van Oudenhove
- Jessica R Biesiekierski
- PubMed: 40138597
- DOI: 10.1002/ueg2.70014
- High evidence
- Clinical
Participants experienced higher tension scores after gluten compared with placebo (p = 0.01 acute; p = 0.05 sub-acute) regardless of the group.
- Effect
- Harmful
- Effect size
- Small
- Significant
- Yes
- Dose
- 16 g/day for 5 days (sub-acute)