Milk Protein and Maintained Blood Phenylalanine Level

Doses used in studies

mg/day: 100 (median 100, IQR 100–100) — 1 study

Time to effect

Median: 4 weeks · IQR 4 weeks–4 weeks · Range 4 weeks–4 weeks — Reported in 1 of 1 study

1 of 1 paper

Impact of Fruit and Vegetable Protein vs. Milk Protein on Metabolic Control of Children with Phenylketonuria: A Randomized Crossover Controlled Trial.

2022-10-13
RCT
Nutrients 14(20)
- Alex Pinto
- Anne Daly
- Júlio César Rocha
- Catherine Ashmore
- Sharon Evans
- Richard Jackson
- Anne Payne
- Mary Hickson
- Anita MacDonald

PubMed: 36296952
DOI: 10.3390/nu14204268

3 Insights on

Maintained Blood Phenylalanine Level

High evidence
Rigorous Journal
Clinical

With milk protein, only 8/16 (50%) tolerated an extra 50 mg/day and only 5/16 (31%) tolerated an additional 100 mg/day of phenylalanine. There was a trend that vegetable protein had less impact on blood phenylalanine control than milk protein, but overall, the differences were not statistically significant (p = 0.152).

Effect: Neutral
Effect size: Small
Significant: No
Dose: additional 50 mg/day phenylalanine then additional 100 mg/day phenylalanine