Pea Protein and Increased Cholecystokinin Level

• Intraduodenal administration of intact pea protein effectively reduces food intake in both lean and obese male subjects.

  • 2011-09-13
  • RCT
  • PloS one 6(9)
  • • Maartje C P Geraedts
    • Freddy J Troost
    • Marjet J M Munsters
    • Jos H C H Stegen
    • Rogier J de Ridder
    • Jose M Conchillo
    • Joanna W Kruimel
    • Ad A M Masclee
    • Wim H M Saris

  • PubMed: 21931864
  • DOI: 10.1371/journal.pone.0024878

  3 Insights on

  • Increased Cholecystokinin Level

  • High evidence
  • Clinical

  CCK levels were increased at 10(p<0.02) and 20(p<0.01) minutes after intraduodenal protein administration (IPA), in obese subjects, compared to lean subjects, but also compared to oral protein administration (OPA)(p<0.04).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  250 mg/kg bodyweight in 0.4 ml/kg bodyweight of water