High Degree of Desensitization After 1 Year of Early-Life Peanut Oral Immunotherapy: Small Children Oral Immunotherapy (SmaChO) Randomized Controlled Trial.
- 2024-05
- RCT · n = 75
- The journal of allergy and clinical immunology. In practice 12(5)
- Carina Uhl
- Susanna Klevebro
- Eva Sverremark-Ekström
- Sandra G Tedner
- Josef Brandström
- Chrystalleni Papageorgiou
- Erik Melén
- Jon R Konradsen
- Caroline Nilsson
- Anna Asarnoj
- PubMed: 38428524
- DOI: 10.1016/j.jaip.2024.02.030
- High evidence
- Clinical
Median tolerated cumulative dose was 2,750 mg (IQR, 275-5,000 mg) peanut protein in the OIT group compared with 2.8 mg (IQR, 0.3-27.8 mg) in the avoidance group (P < .001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- low maintenance dose