Protease and Reduced Breast Swelling

Safety in these studies

Overall tolerabilityNo significant differenceno women experienced adverse events in any of the groups receiving serrapeptase, protease or placebo (low-certainty evidence)
No women experienced adverse events in any of the groups receiving serrapeptase, protease or placebo (low-certainty evidence).
from: Treatments for breast engorgement during lactation.

1 of 1 paper

Treatments for breast engorgement during lactation.

2020-09-18
Systematic Review · n = 2,170
The Cochrane database of systematic reviews 2020(9)
- Irena Zakarija-Grkovic
- Fiona Stewart

PubMed: 32944940
DOI: 10.1002/14651858.cd006946.pub4

3 Insights on

Reduced Breast Swelling

High evidence
Clinical

Protease may reduce breast pain (RR 0.17, 95% CI 0.04, 0.74; low-certainty evidence; 59 women) and breast swelling (RR 0.34, 95% CI 0.15 to 0.79; 59 women; low-certainty evidence)

Effect: Beneficial
Effect size: Large
Significant: No