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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Soy Protein and Reduced Phosphorus Level

Doses used in studies

g/day: 20 (median 20, IQR 20–20) — 1 study

Time to effect

Median: 18.3 months · IQR 15.2 months–21.3 months · Range 12.2 months–24.3 months — Reported in 2 of 2 studies

2 of 2 papers

[Soy protein as part of a low-protein diet is a new direction in cardio- and nephroprotection in patients with 3B-4 stages of chronic kidney disease: prospective, randomized, controlled clinical study].
- 2022-08-04
- RCT · n = 85
- Terapevticheskii arkhiv 94(6)
- - L Y Milovanova
  - M V Taranova
  - A V Volkov
  - S Y Milovanova
  - V D Beketov
- PubMed: 36286853
- DOI: 10.26442/00403660.2022.06.201567
8 Insights on
- Reduced Phosphorus Level
- High evidence
- Clinical
increase in phosphorus (-10.3% vs +13.0%; p=0.029)
Effect
Beneficial
Effect size
Small
Significant
Yes
Soy protein supplementation in men following radical prostatectomy: a 2-year randomized, placebo-controlled clinical trial.
- 2021-04
- RCT · n = 50
- The American journal of clinical nutrition 113(4)
- - Maarten C Bosland
  - Erika Enk
  - Joanne Schmoll
  - Michael J Schlicht
  - Carla Randolph
  - Ryan J Deaton
  - Hui Xie
  - Anne Zeleniuch-Jacquotte
  - Ikuko Kato
- PubMed: 33564828
- DOI: 10.1093/ajcn/nqaa390
12 Insights on
- Reduced Phosphorus Level
- High evidence
- Clinical
Compared with casein, soy supplementation did not affect body weight, blood pressure, serum total cholesterol, calcium, phosphorus, and thyroid hormones.
Effect
Neutral
Effect size
Small
Significant
No
Dose
20 g/day providing 41 mg/day total isoflavones and 23 mg/day genistein