Whey Protein and Increased Muscle Protein Synthesis

• The Effect of β-Hydroxy-β-Methyl Butyrate (HMB) upon Acute Fed-State Muscle Protein Turnover in Older Men and Women: A Randomized Double-Blind Controlled Crossover Clinical Trial.

  • 2026-04-30
  • RCT · n = 24
  • Nutrients 18(9)
  • • Kenneth Smith
    • Kenneth Smith
    • Haitham Abdullah
    • Supreeth Rudrappa
    • Amanda Gates
    • Jonathan Lewis
    • Iskandar Idris
    • Joseph J Bass
    • Hannah Crossland
    • Daniel J Wilkinson
    • Min Tian
    • Deborah S Hustead
    • Geraldine E Baggs
    • Suzette L Pereira
    • Bethan E Phillips
    • Philip J Atherton

  • PubMed: 42124050
  • DOI: 10.3390/nu18091449

  1 Insight on

  • Increased Muscle Protein Synthesis

  • High evidence
  • Rigorous Journal
  • Elderly

  In all subjects, both interventions displayed significant increases in MPS in response to feeding [fasted to 3 h-fed change ... p < 0.05].

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  40 g whey protein