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Exploring Probiotic Strains for Managing Celiac Disease Symptoms

Discuss the potential benefits of probiotics like Lactobacillus and Bifidobacterium for celiac disease management. Explore their roles in gluten peptide digestion and immune response modulation, emphasizing the need for professional consultation before use.


  • Best probiotic for celiac disease?

    Hi

    I would like to know which probiotic strains are best or at least recommended, for celiac disease.

    Thank you.

  • For individuals with celiac disease, certain probiotic strains have shown potential in managing the condition due to their ability to interact with the gut microbiota and potentially hydrolyze harmful gluten peptides.

    1. Lactobacillus and Bifidobacterium: These genera are often highlighted in studies for their protective properties. They can digest or alter gluten polypeptides and exert protective effects on epithelial cells from damage caused by gliadin1. Specifically, Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 have been found to positively modify the immune response in children with CD autoimmunity2.

    2. Bifidobacterium breve: This strain has demonstrated beneficial effects by reducing pro-inflammatory cytokines in children with celiac disease who are on a gluten-free diet2.

    The use of these probiotics in conjunction with a gluten-free diet may provide symptomatic relief and assist in the management of celiac disease. However, consulting with a healthcare provider before starting any new supplement regimen is always recommended.

    Footnotes

    1. Luís Fernando de Sousa Moraes, "Intestinal Microbiota and Probiotics in Celiac Disease," PubMed Central, July 2014.

    2. Mostafa Hossam-Eldin Moawad, "Efficacy of probiotics supplementation in amelioration of celiac disease symptoms and enhancement of immune system," PubMed Central, November 2023. 2

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