Celiac disease significantly impairs nutrient absorption due to damage to the small intestinal mucosa caused by an immune response to gluten¹². Adhering to a gluten-free diet (GFD), the primary treatment for celiac disease, can also lead to nutritional imbalances because gluten-free products often lack essential nutrients³.

Key nutrients commonly deficient in individuals with celiac disease include:

1. Iron: Iron deficiency is prevalent, often resulting in anemia⁴.
2. Calcium and Vitamin D: Necessary for bone health, these are often deficient, which can affect bone density⁵.
3. B Vitamins (B6, B12, and Folate): These are critical for overall health, including neurological function⁶.
4. Zinc: Important for immune function and metabolism, zinc levels are often low⁷.
5. Magnesium: Essential for many biochemical reactions and muscle function⁸.

Supplementation can help manage these deficiencies effectively:

• Iron supplements may be recommended particularly for those diagnosed with anemia.
• Calcium and Vitamin D supplementation can support bone health.
• B Vitamins: A combination of folic acid, cyanocobalamin (B12), and pyridoxine (B6) has shown to improve the wellbeing of celiac patients⁹.
• Zinc and Magnesium supplements can help restore normal levels.

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Footnotes

1. PubMed ↩

2. PubMed Central ↩

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9. PubMed ↩