When it comes to addressing white or gray hair, commonly known as premature hair graying (PHG), several nutrients and supplements have shown promise in preventing or potentially reversing the condition based on scientific research. Here are some of the notable ones:

1. Biotin (Vitamin B7): Biotin is a water-soluble vitamin that supports hair health. Several studies have suggested that biotin supplementation can aid in improving the health and appearance of hair¹.

2. Calcium Pantothenate (Vitamin B5): This vitamin is known to support healthy hair pigmentation and has been used in combination with biotin to address PHG².

3. Vitamin B12: Deficiency in vitamin B12 is often linked to loss of hair pigment. Ensuring adequate levels of this vitamin might help in reversing the graying process³.

4. Iron: Iron deficiency, particularly iron deficiency anemia, has been identified as a causative factor in PHG. Supplementing with iron, especially in cases of identified deficiency, may help in treating PHG⁴.

5. Copper and Other Trace Elements: Copper deficiency has been correlated with hair depigmentation. Supplements that include copper, calcium, and other trace elements are sometimes used to address this issue⁵.

If you are considering taking supplements to address premature hair graying, it's advisable to consult with a healthcare professional for personalized advice and appropriate dosages.

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Footnotes

1. Prospective Analytical Controlled Study Evaluating Serum Biotin, Vitamin B12, and Folic Acid in Patients with Premature Canities. ↩

2. Reversal of Premature Hair Graying Treated with a Topical Formulation Containing α-Melanocyte-Stimulating Hormone Agonist (Greyverse Solution 2%). ↩

3. A Case of Premature Hair Graying Treated with Ferrous Sulfate. ↩

4. Relationship between Trace Elements and Premature Hair Graying. ↩

5. Factors Associated with Premature Hair Graying in a Young Indian Population. ↩