Nutrafol is a popular nutraceutical supplement designed to promote hair growth and improve hair quality. It is composed of a proprietary blend of phytoactives known as the Synergen Complex®, which includes ingredients like curcumin, piperine, ashwagandha, saw palmetto, and tocotrienols¹².

Key Components of Nutrafol:

• Curcumin: An anti-inflammatory and immunomodulating agent that helps inhibit NF-kb and reduce inflammatory cytokines involved in hair follicle regression¹.
• Piperine: Enhances curcumin's bioavailability, greatly increasing its effectiveness².
• Ashwagandha: An adaptive herb known for reducing stress and its related impacts on hair health².
• Saw Palmetto: Inhibits dihydrotestosterone (DHT), a hormone linked to hair loss².
• Tocotrienols: A form of Vitamin E with potent antioxidant properties².

Clinical Evidence:

Nutrafol has been studied for its effects on hair growth. One clinical trial found that daily intake resulted in significant improvements in the number of terminal and vellus hairs after 90 and 180 days compared to a placebo¹. Subjects also reported improvements in hair growth, volume, thickness, and overall hair quality, along with decreased anxiety and other wellness parameters¹.

Safety:

The product has been shown to be safe in clinical studies with no reported adverse events¹. However, like all supplements, it should be taken according to prescribed dosages, and it's advisable to consult with a healthcare provider before starting any new supplement regimen.

Additional Considerations:

Although Nutrafol's composition includes various micronutrients and botanical compounds, one should be careful about excessive supplementation of certain vitamins and minerals, as high doses have been linked to increased cancer risks in some studies³.

Footnotes

1. Glynis Ablon, "A Six-Month, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of a Nutraceutical Supplement for Promoting Hair Growth in Women With Self-Perceived Thinning Hair," PubMed. ↩ ↩² ↩³ ↩⁴ ↩⁵

2. Christina Ring, "Nutraceuticals for Androgenetic Alopecia," NCBI. ↩ ↩² ↩³ ↩⁴ ↩⁵

3. Emily K. Burns, "Risks of Skin, Hair, and Nail Supplements," NCBI. ↩