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Does Lactobacillus rhamnosus GG effectively reduce dermatitis?

This chat examines whether Lactobacillus rhamnosus GG helps with dermatitis. Based on one RCT showing no significant improvement, the evidence is insufficient to support its use for this condition.

  • Does Lactobacillus rhamnosus GG actually help with reducing dermatitis, or is there not enough evidence to say it works?

  • Based on the evidence currently available, the answer is that there isn't enough evidence to conclude that Lactobacillus rhamnosus GG (LGG) effectively reduces dermatitis.

    Here's what Pillser's research database shows1:

    Key Findings

    DetailSummary
    Total studies1 (randomized controlled trial)
    Beneficial0 studies
    Neutral1 study
    Harmful0 studies

    The single available study was a 2020 randomized, double-blind, placebo-controlled trial investigating LGG in infants with cow's milk protein allergy2. It used a dose of 1×10⁹ CFU/day and found:

    "No significant improvement was observed in... dermatitis (p = 0.071)."

    While the p-value of 0.071 was close to the conventional threshold for statistical significance (p < 0.05), it did not reach it, meaning the result was considered neutral — the effect was small and not statistically significant2.

    Bottom Line

    With only one study available showing a non-significant result, the evidence base is far too thin to confidently say that Lactobacillus rhamnosus GG helps with dermatitis. More high-quality trials are needed before any conclusions can be drawn.

    Footnotes

    1. Pillser research database, Lactobacillus rhamnosus GG & Reduced Dermatitis. ↩

    2. "Investigation of the Efficacy of Lactobacillus rhamnosus GG in Infants With Cow's Milk Protein Allergy: a Randomised Double-Blind Placebo-Controlled Trial" (2020), Pillser. ↩ ↩2

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