Top Probiotic Brands with Peer-Reviewed, Double-Blind Studies Showcasing Health Benefits
Discover probiotic brands like Align, Culturelle, and VSL#3 that have conducted double-blind, placebo-controlled studies to validate their health benefits. Learn which strains are backed by rigorous research for gastrointestinal and immune health.
Probiotic brands with double blind studies?
Are there any brands of probiotics that have peer-reviewed double-blind studies proving positive health impacts?Most (all?) prominent brands have information on their sites about the bacterial strands they include and what their potential health benefits are. That's fine, but I can't find one where the company invested in an actual study proving health benefits of their product.
This is even the case for Bened's Neuralli MP, which the company says may positively impact conditions like Parkinson's. The one study on their website on Parkinson's was single arm, open label (see below). https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2021.650053/full
While it's true that many probiotic companies list the strains and potential benefits of their products, few brands undergo the rigorous process of double-blind, placebo-controlled studies to validate their health claims. However, there are some exceptions:
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Align: Align has conducted several double-blind, placebo-controlled studies, particularly involving its Bifidobacterium longum subsp. infantis 35624 strain, which is shown to help with irritable bowel syndrome (IBS).
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Culturelle: The Lactobacillus rhamnosus GG strain used in Culturelle probiotics is one of the most studied, with several double-blind, placebo-controlled trials supporting its efficacy in gastrointestinal health and immune support.
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VSL#3 (now known as Visbiome): VSL#3 has a variety of studies, including double-blind, placebo-controlled trials, showing positive impacts on conditions such as ulcerative colitis and IBS.
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Florastor: Saccharomyces boulardii, the active ingredient in Florastor, has been subjected to numerous studies, including double-blind, placebo-controlled trials, demonstrating benefits for gastrointestinal health.
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Bio-K+: This brand has clinical studies, including double-blind, placebo-controlled trials, showing benefits in gastrointestinal health, particularly for antibiotic-associated diarrhea.
Double-blind, placebo-controlled studies are considered the gold standard in clinical research because they minimize bias and provide more reliable results. When evaluating probiotic supplements, it's crucial to look for such studies to confirm the efficacy of the product.
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