For liver health, several supplements have shown potential benefits based on scientific research:

1. Milk Thistle (Silymarin): Milk thistle is one of the most common and well-researched supplements for liver health. The active component, silymarin, has antioxidant, anti-inflammatory, and antifibrotic properties. It has been used for conditions like fatty liver disease, hepatitis, and cirrhosis¹².

2. Vitamin E: There is evidence that vitamin E can decrease the NAFLD activity score in patients with nonalcoholic fatty liver disease (NAFLD), although it might not improve fibrosis³.

3. Licorice Root Extract (Glycyrrhizin): This has anti-inflammatory and cytoprotective effects that may benefit liver function, particularly in chronic hepatitis C and subacute hepatic failure².

4. Phyllanthus: This herbal preparation shows potential in clearing HBV markers with no major adverse effects. However, more rigorous clinical trials are needed to determine its efficacy on long-term outcomes like cirrhosis or liver cancer².

5. Omega-3 Fatty Acids: Omega-3 fats can help reduce liver fat levels and inflammation, making them beneficial for NAFLD management⁴.

6. Curcumin and Resveratrol: Polyphenols like curcumin (from turmeric) and resveratrol (found in grape skin) have antioxidant and anti-inflammatory properties that may support liver health⁴.

While these supplements can support liver health, it is important to consult with a healthcare provider before starting any new supplement to ensure safety and appropriateness for your specific health needs.

Footnotes

1. Ted George O. Achufusi, "Milk Thistle," NCBI Bookshelf ↩

2. Radha K Dhiman, "Herbal medicines for liver diseases," PubMed ↩ ↩² ↩³

3. Ahmed M Baradeiya, "Can Nutritional Supplements Benefit Patients With Nonalcoholic Steatohepatitis and Nonalcoholic Fatty Liver Disease?" NCBI ↩

4. Examine.com, "Supplements of most interest for liver health" ↩ ↩²