Transitioning from Methylcobalamin to Hydroxocobalamin: Dosage and Folic Acid Advice
This conversation discusses switching from 5000 μg methylcobalamin to 1000 μg hydroxocobalamin for Vitamin B12 supplementation. It covers considerations for dosage adjustments and provides general guidelines for folic acid intake, emphasizing consulting with healthcare professionals.
Unsure on measurements
I was taking 5000ųg of methylcobalamin sublingual but I couldn’t tolerate the methyl so I have ordered some hydroxocobalamin. The tablets are only 1000ųg each, should I be taking 5 a day spaced out throughout the day? Also how much folic acid should I be taking?
When switching from methylcobalamin to hydroxocobalamin for Vitamin B12 supplementation, it is important to consider the differences in bioavailability and dosing. Hydroxocobalamin, like other forms of Vitamin B12, is available in larger dosages for direct absorption. If you are moving from 5000 µg of methylcobalamin to 1000 µg tablets of hydroxocobalamin, you might not directly need the same high dosage, as hydroxocobalamin can be effective even in smaller doses due to its stability and prolonged retention in the body1. However, individual needs can vary greatly, so it is essential to consult with a healthcare provider to determine the appropriate dosage for your situation.
Regarding folic acid, the recommended dosage for adults is generally 400 micrograms (mcg) daily2. However, for individuals with specific conditions or increased nutritional requirements, such as pregnancy, the recommended intake can be higher (600-800 mcg per day during pregnancy)3. Always discuss with a healthcare professional before making changes to your supplementation routine.
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