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Understanding Immune Modulation: Effects of Lion's Mane, Reishi, and Turkey Tail Mushrooms

This chat explores how Lion's Mane, Reishi, and Turkey Tail mushrooms modulate the immune system, focusing on their influence towards Th1 or Th2 responses. Expert references highlight the immune-boosting properties of these medicinal mushrooms.


  • Lion's mane induces Th1 response or Th2 response?

  • Lion's mane (Hericium erinaceus) primarily modulates the immune system towards a Th1 response. Th1 cytokine patterns, such as IFN-γ, IL-12, and TNF-α, stimulate the cellular immune response, which is essential for combatting infections and cancer cells12.

    Footnotes

    1. Giuseppe Venturella, "Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials," PubMed Central, 2021.

    2. Alena G. Guggenheim, "Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology," PubMed Central, 2021.

  • Reishi induces Th1 response or Th2 response?

  • Reishi (Ganoderma lucidum) primarily modulates the immune system towards a Th1 response. It has immunomodulatory properties that include the activation of cytotoxic T cells, B lymphocytes, dendritic cells, macrophages, NK cells, and cytokines such as IL-2 and TNF-α, which are associated with the Th1 response12.

    Footnotes

    1. Giuseppe Venturella, "Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials," PubMed Central, 2021

    2. Alena G. Guggenheim, "Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology," PubMed Central, 2021

  • Turkey tail fruit body induces Th1 response or Th2 response?

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