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Comprehensive Overview of L-Theanine: Benefits, Uses, and Supporting Studies

This chat explores L-theanine, an amino acid in green tea, highlighting its benefits like stress reduction, cognitive enhancement, and immune support. Key studies on its effects on mood, neuroprotection, cardiovascular health, and immune function are discussed with recommendations for supplementation.


  • theanine?

  • L-theanine is an amino acid predominantly found in green tea, known for its numerous health benefits, including stress reduction, cognitive enhancement, and immune support.

    Benefits and Uses of L-theanine

    1. Stress and Anxiety Reduction:
      Several systematic reviews have shown that L-theanine helps manage stress and anxiety. Supplementing with 200-400 mg/day of L-theanine can significantly reduce stress and anxiety in stressful conditions12.

    2. Mood and Cognitive Function:
      L-theanine enhances mood and cognitive functions, such as memory and attention, by increasing alpha brainwave activity, which promotes relaxation without drowsiness3. It also improves depressive symptoms, sleep quality, and cognitive impairments in patients with major depressive disorder4.

    3. Neuroprotective Effects:
      L-theanine possesses neuroprotective properties, aiding in the mitigation of neurodegenerative conditions and improving cognitive function in middle-aged and older subjects5.

    4. Cardiovascular and Metabolic Health:
      The compound has been shown to have cardiovascular protective effects by inhibiting blood pressure increases under stress, and it also plays a role in metabolic regulation6.

    5. Immune System Support:
      L-theanine enhances immune functions, which can help in reducing the immunosuppressive effects of stress and strenuous exercise, and it may lower the risk of colds and influenza7.

    Summary of Key Sources

    • Systematic Review on Anxiety and Stress: L-theanine supplementation (200-400 mg/day) was found effective in reducing stress and anxiety in stressful conditions1.
    • Open-label Study on Major Depressive Disorder: Chronic administration of L-theanine exhibited multiple beneficial effects on depressive symptoms, anxiety, and sleep disturbance4.
    • Neuroprotective Review: Highlighted the antioxidant, anti-inflammatory, and neuroprotective properties of L-theanine6.
    • Immune Function Review: Documented L-theanine's role in immunoregulation and protection against pathogens7.

    For more detailed product recommendations or specific brands containing L-theanine, feel free to ask!

    Footnotes

    1. Examine.com: Theanine Supplement Benefits 2

    2. PubMed: The Effects of Green Tea Amino Acid L-Theanine Consumption on Stress and Anxiety

    3. PubMed: L-theanine and Its Effect on Mental State

    4. PubMed: Effects of L-theanine in Major Depressive Disorder 2

    5. PubMed: Effects of L-Theanine on Cognitive Function

    6. NCBI: L-Theanine: A Unique Functional Amino Acid 2

    7. NCBI: L-Theanine and Immunity: A Review 2

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