To optimize muscle growth, several supplements have shown potential benefits based on current research:

1. Protein Supplements: Protein is essential for muscle repair and growth. Whey, casein, and soy protein are popular options. Studies show that protein supplementation, when combined with resistance training, can significantly increase muscle size and strength[^1^][^2^].

2. Creatine: Creatine is one of the most researched and effective supplements for muscle growth. It enhances strength and exercise performance and accelerates muscle mass gain by increasing muscle creatine content[^3^][^4^].

3. Beta-Alanine: This amino acid can help improve performance in high-intensity exercise by reducing muscle fatigue. It works by increasing muscle carnosine levels, which help buffer acid in muscles[^5^].

4. Branched-Chain Amino Acids (BCAAs): Comprising leucine, isoleucine, and valine, BCAAs are vital for muscle protein synthesis and reducing exercise-induced muscle damage[^3^].

5. Beta-Hydroxy Beta-Methylbutyrate (HMB): A metabolite of the amino acid leucine, HMB may help reduce muscle loss during periods of muscle atrophy and support muscle growth when combined with resistance training[^3^][^6^].

Consulting with a healthcare provider before starting any supplementation is advisable to ensure safety and appropriateness based on individual health conditions and goals.