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In-Depth Exploration of Ginkgo Biloba: Benefits, Uses, and Safety Considerations

Discover the various health benefits of Ginkgo biloba, including cognitive improvement, neuroprotection, and cardiovascular health, along with safety and side effects. Learn about its potential applications and considerations for use.


  • Gingko biloba

  • Ginkgo biloba is a popular herbal supplement known for its potential benefits in cognitive function, neuroprotection, and other health conditions. Here are some key points about its uses and effects:

    Cognitive Function and Memory

    Ginkgo biloba extract (GBE) is widely investigated for its potential to improve memory and cognitive function, especially in the elderly and those with Alzheimer's disease1. Some studies suggest that GBE can stabilize and improve cognitive performance and social functioning in dementia patients for up to one year2. However, the efficacy in the prevention and treatment of dementia remains controversial, with some trials showing positive results and others not confirming significant benefits34.

    Neuroprotection

    GBE has neuroprotective properties thanks to its antioxidant and anti-inflammatory actions. It's been implicated in the treatment of Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions5. The extract contains flavonoid glycosides and terpene lactones, which contribute to its beneficial effects6.

    Cardiovascular and Vascular Health

    Ginkgo biloba may improve blood circulation and has been suggested to help with vasoocclusive disorders, stroke recovery, and reducing symptoms of intermittent claudication7. Its antiplatelet and hemorrheologic actions help improve microcirculation and reduce blood viscosity8.

    Other Potential Benefits

    GBE has been studied for its possible effects on tinnitus, macular degeneration, and some psychiatric disorders9. It may also help alleviate symptoms associated with stress, improve mood, and protect against free radical damage10.

    Safety and Side Effects

    While generally considered safe, Ginkgo biloba can interact with anticoagulant medications and may cause side effects such as headaches, dizziness, gastrointestinal disturbances, and allergic skin reactions11. Its use should be carefully monitored, especially in individuals with bleeding disorders or those on blood-thinning medications12.

    For a detailed understanding, please refer to the sources cited:

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    Footnotes

    1. Singh et al., 2024

    2. Diamond, 2024

    3. Mahadevan, 2024

    4. Field, 1998

    5. Barbalho, 2022

    6. Isah, 2014

    7. Brondino, 2013

    8. Field, 1998

    9. Brondino, 2013

    10. Mahadevan, 2024

    11. Nguyen, 2024

    12. Field, 1998

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