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Magnesium L-threonate: Cognitive Benefits and Uses Explored

The conversation dives into the benefits of Magnesium L-threonate, an effective supplement for brain health and cognition. It also clarifies the role of Eloquis, which is outside the supplement scope, as an anticoagulant medication.

  • magnesium L threonate

  • Magnesium L-threonate: Benefits and Uses

    What is Magnesium L-threonate?

    Magnesium L-threonate (MgT) is a compound that has been developed to boost magnesium levels in the brain more effectively than other magnesium forms. It is known for its high bioavailability, making it particularly effective for brain health.

    Cognitive Benefits

    1. Memory and Cognition Improvement: Studies have shown that Magnesium L-threonate can significantly improve memory and cognitive functions12. It has been used to enhance learning abilities, working memory, and both short-term and long-term memory3.

    2. Neuroprotective Effects: MgT has been demonstrated to protect against neurodegenerative conditions such as Alzheimer's and Parkinson's diseases. It helps by modulating the microbiota-gut-brain axis and reducing oxidative stress and inflammation45.

    3. Chronic Pain and Memory Deficits: In animal models, MgT has been effective in preventing and restoring memory deficits associated with chronic neuropathic pain by inhibiting tumor necrosis factor-alpha (TNF-α) and by improving hippocampal functions6.

    Additional Uses

    1. Oxidative Stress Damage Prevention: Magnesium L-threonate has exhibited a neuroprotective effect against oxidative stress, which is associated with neurodegenerative disorders7.

    2. Parkinson's Disease: Treatment with MgT has been shown to elevate magnesium levels in the cerebrospinal fluid and attenuate motor deficits and dopamine neuron loss in mouse models of Parkinson's disease8.

    MgT seems to be a promising supplement not only for enhancing cognitive functions but also for offering neuroprotection against various brain disorders.

    Footnotes

    1. Chengxiang Zhang et al., "A Magtein®, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults," PubMed Central, 2022. PubMed ↩

    2. Wang Liao et al., "Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis," PubMed Central, 2024. PubMed ↩

    3. Inna Slutsky et al., "Enhancement of learning and memory by elevating brain magnesium," PubMed, 2010. PubMed ↩

    4. Wang Liao, "Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis," PMC, 2021. PubMed ↩

    5. Ying Xiong, "Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer’s disease mouse model," PMC, 2022. PMC ↩

    6. Jun Wang, "Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-α," PubMed, 2024. PubMed ↩

    7. Ying Xiong, "Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer’s disease mouse model," PMC, 2022. PMC ↩

    8. Yanling Shen, "Treatment Of Magnesium-L-Threonate Elevates The Magnesium Level In The Cerebrospinal Fluid And Attenuates Motor Deficits And Dopamine Neuron Loss In A Mouse Model Of Parkinson’s disease," PMC, 2019. PMC ↩

  • Eloquis

  • It appears that you are asking about Eloquis, which is actually a prescription medication (apixaban) used as an anticoagulant to prevent blood clots. This topic does not pertain to dietary supplements, which is my area of expertise.

    If you have any questions about dietary supplements or nutrition, feel free to ask!

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