Memory loss can be a concerning issue, and several supplements are commonly discussed for their potential cognitive benefits. Below are some supplements that have been researched for their potential in supporting memory and cognition:

1. B Vitamins:

   • Vitamins such as B6, B9 (folic acid), and B12 have been explored for their roles in brain health. These vitamins help in reducing homocysteine levels, which is associated with a decreased risk of cognitive decline¹².

2. Omega-3 Fatty Acids:

   • Omega-3s, particularly DHA (docosahexaenoic acid), are crucial for brain health. They have anti-inflammatory effects and help in maintaining the structure and function of brain cells³.

3. Antioxidants:

   • Vitamins C and E, along with other antioxidants, have been found to protect brain cells from oxidative stress. Long-term supplementation with antioxidant vitamins showed potential benefits for cognitive function⁴⁵.

4. Ginkgo Biloba:

   • This herb is frequently used to enhance cognitive function and improve memory, particularly in older adults. It may improve blood flow to the brain and act as an antioxidant⁶.

5. Phosphatidylserine:

   • This phospholipid is a component of cell membranes and has been investigated for its potential to support cognitive functions, including memory and attention⁷.

6. Curcumin:

   • The active compound in turmeric, curcumin, has anti-inflammatory and antioxidant properties, which may help in protecting the brain from cognitive decline⁸.

7. Lion’s Mane Mushroom:

   • This mushroom has shown promise in promoting nerve growth factor (NGF) synthesis and improving cognitive functions⁹.

8. Resveratrol:

   • Found in red wine and grapes, resveratrol may have neuroprotective effects that help in maintaining cognitive health¹⁰.

These are some of the key supplements that have been investigated for memory loss and cognitive support. If you are considering taking any of these supplements, it may be helpful to discuss it with a healthcare provider for personalized advice and to ensure there are no contraindications with any medications you may be taking.

Would you like to see a list of products for any of these supplements?

Footnotes

1. Wang, Z., "B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis," PubMed, 2022. ↩

2. Rutjes, A. W. S., "Vitamin and mineral supplementation for maintaining cognitive function," PubMed, 2018. ↩

3. Madireddy, S., "Most Effective Combination of Nutraceuticals for Improved Memory," PMC, 2025. ↩

4. Tardy, A.-L., "Vitamins and Minerals for Energy, Fatigue and Cognition," Nutrients, 2020. ↩

5. Hersant, H., "Over the Counter Supplements for Memory," PubMed, 2023. ↩

6. Snow, A. D., "In vitro comparison of major memory-support dietary supplements," PMC, 2021. ↩

7. Grima, N. A., "The effects of multivitamins on cognitive performance," PubMed, 2011. ↩

8. Fekete, M., "Improving Cognitive Function with Nutritional Supplements," PMC, 2023. ↩

9. Hersant, H., "Over the Counter Supplements for Memory: A Review," PubMed, 2023. ↩

10. Fekete, M., "Improving Cognitive Function with Nutritional Supplements," PMC, 2023. ↩