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Understanding Melatonin: Its Role, Uses, and Safety in Sleep Regulation

Explore melatonin, a natural hormone crucial for sleep-wake cycles. Learn about its production, benefits for sleep issues like insomnia and jet lag, and other potential uses. Discover safety recommendations and consult reliable sources for more information.


  • What is melatonin

  • Melatonin is a hormone that naturally occurs in the body and plays a crucial role in regulating sleep-wake cycles12. It is primarily produced by the pineal gland in the brain, with levels rising at night to signal that it is time to sleep and falling during the day to promote wakefulness2.

    Supplemental melatonin is often used to treat sleep problems such as insomnia and jet lag. It can help people fall asleep faster and improve the overall quality of their sleep1. While it is most commonly used for short-term sleep issues, melatonin is also utilized in some cases for longer-term sleep disorders, particularly in children and certain adults13.

    Additionally, melatonin has been explored for other uses, including managing symptoms of depression, chronic pain, and neurodegenerative disorders, although the scientific evidence supporting these uses is not as strong4.

    Melatonin supplements are generally considered safe with a relatively low risk of adverse effects. However, it is typically recommended for short-term use and should be used under the guidance of a healthcare professional34.

    Footnotes

    1. NHS: About Melatonin 2 3

    2. MedlinePlus: Melatonin 2

    3. NCBI: Melatonin - StatPearls 2

    4. PubMed Central: Melatonin - Pharmacology, Functions, and Therapeutic Benefits 2

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