A probiotic lozenge administered medical device and its effect on salivary mutans streptococci and lactobacilli.
- 2007-08-21
- International Journal of Paediatric Dentistry 18(1)
- E. Çaglar
- O. Kuscu
- S. Cildir
- Senem Selui Kuvvetli
- N. Sandalli
- PubMed: 18086024
- DOI: 10.1111/J.1365-263X.2007.00866.X
Study Design
- Type
- Randomized Controlled Trial (RCT)
- Sample size
- n = 20
- Population
- Healthy young women with high Streptococcus mutans counts
- Methods
- Randomized Controlled Trial
- Highly Cited
Abstract
Background: Previous studies have suggested that lactobacilli-derived probiotics in dairy products may affect oral ecology, but the effects of different delivery methods have received little attention.
Aim: The aim of the present study was to investigate the effect of the probiotic Lactobacillus reuteri, delivered by a new medical device, on the levels of salivary mutans streptococci and lactobacilli in young women with high Streptococcus mutans counts.
Design: This is a randomized, double-blind, placebo-controlled study involving 20 healthy young women (aged 20 years): 10 as subjects and 10 as controls. The study subjects (Group A) sucked the medical device containing the probiotic lozenge with L. reuteri ATCC 55730/L. reuteri ATCC PTA 5289 (1.1 x 10(8) CFU) once daily for 10 days, while the control subjects (Group B) received placebo medical devices without bacteria. Salivary mutans streptococci and lactobacilli were enumerated with chair-side kits at baseline and 1 day after the final ingestion.
Results: Salivary S. mutans levels in the probiotic test group were significantly reduced, with statistical significance of reduction (P < 0.05).
Conclusions: A short-term daily ingestion of lactobacilli-derived probiotics delivered via medical device containing probiotic lozenge reduced the levels of salivary mutans.