A Topical Gel From Flax Seed Oil Compared With Hand Splint in Carpal Tunnel Syndrome: A Randomized Clinical Trial.
- 2016-12-01
- Journal of evidence-based complementary & alternative medicine 22(3)
- Mohammad Setayesh
- Amir Reza Sadeghifar
- Nozar Nakhaee
- Mohammad Kamalinejad
- Hossein Rezaeizadeh
- PubMed: 27909031
- DOI: 10.1177/2156587216677822
Study Design
- Type
- Randomized Controlled Trial (RCT)
- Population
- Forty-nine patients, 96 hands, with mild to moderate idiopathic carpal tunnel syndrome
- Methods
- Randomized clinical trial; one group treated by topical gel and the other group by hand splint
- Blinding
- Open-label
This study compared the therapeutic effect of flax seed oil topical gel and hand splint in the treatment of carpal tunnel syndrome. This study was a randomized clinical trial. Forty-nine patients, 96 hands, with mild to moderate idiopathic carpal tunnel syndrome were divided into 2 groups randomly. One group was treated by topical gel and the other group by hand splint. Intensity of symptoms and function before and after intervention was measured via Boston Carpal Tunnel Questionnaire. After intervention, the ANCOVA showed a significant difference between the symptom and function scores of the 2 groups. In both cases, recovery was higher in the gel group ( P < .001). The topical use of flax seed oil gel is more effective in the improvement of symptoms and function of patients with mild to moderate carpal tunnel syndrome as compared with hand splint, and it can be introduced as an effective treatment.
Research Insights
After intervention, the ANCOVA showed a significant difference between the symptom and function scores of the 2 groups. In both cases, recovery was higher in the gel group (P < .001).
- Effect
- Beneficial
- Effect size
- Moderate
- Dose
- topical gel (no specific dose reported)
After intervention, the ANCOVA showed a significant difference between the symptom and function scores of the 2 groups. In both cases, recovery was higher in the gel group (P < .001).
- Effect
- Beneficial
- Effect size
- Moderate
- Dose
- topical gel (no specific dose reported)