[Advances in research on chemical composition of Picrorhiza scrophulariiflora and P. kurroa and their biological activities].
- 2021-12-01
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 46(23)
- Li-Zheng Ma
- Li-Ping Kang
- Tie-Gui Nan
- Zhi-Lai Zhan
- Lan-Ping Guo
- PubMed: 34951239
- DOI: 10.19540/j.cnki.cjcmm.20210708.601
Study Design
- Type
- Review
At present, 141 compounds have been isolated from Picrorhiza scrophulariiflora and P. kurroa of the Scrophulariaceae plants, including 46 iridoid glycosides, 29 tetracyclic triterpenoids, 25 phenylpropanoids, and 11 phenylethanoid glycosides. Pharmacological studies have demonstrated that they have liver-, heart-, brain-, kidney-, and nerve cells-protecting effects as well as anti-tumor, anti-inflammatory, anti-bacterial, anti-asthma, anti-diabetic, immunomodulatory, and blood lipid-lowering activities. This article reviews the chemical components and pharmacological activities of P. scrophulariiflora and P. kurroa, aiming to provide a basis for the in-depth research, development, and utilization of the two plants.