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Anticholesteremic property of Lactobacillus acidophilus yogurt fed to mature boars.

  • 1989-04-01
  • Journal of Animal Science 67(4)
    • A. D. Danielson
    • E. R. Peo
    • K. Shahani
    • A. Lewis
    • P. Whalen
    • M. Amer

Abstract

Three strains of Lactobacilus acidophilus (LA) were isolated from the feces of mature boars that were not being fed antibiotics from the Nebraska Gene Pool (NGP). All three LA isolates were screened in vitro for anticholesteremic and antimicrobial activities. One strain, LA16, caused the greatest reduction in cholesterol and inhibited both Bacillus subtilis and Escherichia coli the most. LA16 was used to produce 16, 18.9-liter quantities of acidophilus yogurt (AY), over a period of 8 wk, for use as a feed ingredient in diets for the NGP boars. Colony forming units (cfu), pH, protein, energy, Ca and P were consistent across all 16 batches of yogurt. All of the 18 boars were fed a high-cholesterol diet for a period of 56 d at a rate of 2.268 kg/(hd.d) to furnish 6.661 g/(hd.d) of cholesterol. Nine of the boars then were fed 1.81 kg/(hd.d) of a second diet that was supplemented with .454 kg/(hd.d) of AY. The other nine boars were fed the original diet. Cholesterol intake was the same for the two dietary treatments. Blood samples were collected weekly from the brachial-jugular region and the sera were analyzed for lipids. Acidophilus yogurt reduced serum cholesterol (P less than .01) and low density lipoproteins (P less than .08), but it had no effect on serum triglycerides (P greater than .23) or on high density lipoproteins (P greater than .11).

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactobacillus acidophilus LA-02No Change in High Density LipoproteinsNeutral
Small
Lactobacillus acidophilus LA-02No Change in Serum TriglyceridesNeutral
Small
Lactobacillus acidophilus LA-02Reduced Low-Density Lipoprotein LevelBeneficial
Moderate
Lactobacillus acidophilus LA-02Reduced Serum Cholesterol LevelsBeneficial
Large
Lactobacillus acidophilus LA1No Change in High Density LipoproteinsNeutral
Small
Lactobacillus acidophilus LA1No Change in Serum TriglyceridesNeutral
Small
Lactobacillus acidophilus LA1Reduced Low-Density Lipoprotein LevelBeneficial
Moderate
Lactobacillus acidophilus LA1Reduced Serum Cholesterol LevelsBeneficial
Large
Lactobacillus acidophilus La-14No Change in High Density LipoproteinsNeutral
Small
Lactobacillus acidophilus La-14No Change in Serum TriglyceridesNeutral
Small
Lactobacillus acidophilus La-14Reduced Low-Density Lipoprotein LevelBeneficial
Moderate
Lactobacillus acidophilus La-14Reduced Serum Cholesterol LevelsBeneficial
Large

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