Assessment of Probiotic Properties of Lactobacillus salivarius Isolated From Chickens as Feed Additives
- 2020-07-17
- Frontiers in Veterinary Science 7
- Jian Wang
- M. Ishfaq
- Yuesheng Guo
- Chunli Chen
- Jichang Li
- PubMed: 32766298
- DOI: 10.3389/fvets.2020.00415
Abstract
The continued use of sub-therapeutic antibiotics as feed additives in the poultry industry improved health and growth performance. However, the resulting antibiotic resistance increasingly becomes a major threat to public health. Probiotics are promising alternatives for the antibiotics used in poultry industry. The aim of this study was to evaluate the probiotic properties of Lactobacillus salivarius as feed additive in chickens. White leghorn chickens were randomly assigned to experimental groups. Effects of Lactobacillus salivarius supplementation on growth performance, resistance to Escherichia coli O78 challenge and heat-stress, and immune response after vaccinated with attenuated infectious bursal disease virus (IBDV) vaccine were determined. The results showed that Lactobacillus salivarius supplementation improved growth performance, such as weight and longer shank length, increased relative weights of the immune organs and decreased concentrations of odor-causing compounds. In addition, Lactobacillus salivarius supplementation alleviated organ injury caused by Escherichia coli O78 challenge and heat stress. Furthermore, Lactobacillus salivarius results in enhanced immune response after IBDV vaccine immunization, enhanced specific antibody and IFN-γ production, and lymphocyte proliferation. Our results revealed a tremendous potential of Lactobacillus salivarius as antibiotics' substitute in poultry production.
Keywords: Escherichia coli; Lactobacillus salivarius; growth performance; heat stress; oxidative stress.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus Salivarius | Enhanced Immune Response After IBDV Vaccination | Beneficial | Large |
| Lactobacillus Salivarius | Improved Growth Performance | Beneficial | Large |
| Lactobacillus Salivarius | Increased Relative Weight of Immune Organs | Beneficial | Moderate |
| Lactobacillus Salivarius | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus Salivarius | Reduced Organ Injury from Escherichia coli | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Alleviated Organ Injury | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Improved Growth Performance | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Improved Immune Response | Beneficial | Large |
| Lactobacillus salivarius BLIS K12 | Increased Relative Weight of Immune Organs | Beneficial | Moderate |
| Lactobacillus salivarius BLIS K12 | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius CRL 1328 | Enhanced Immune Response After IBDV Vaccination | Beneficial | Large |
| Lactobacillus salivarius CRL 1328 | Improved Growth Performance | Beneficial | Large |
| Lactobacillus salivarius CRL 1328 | Increased Relative Weight of Immune Organs | Beneficial | Moderate |
| Lactobacillus salivarius CRL 1328 | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius HA-118 | Alleviated Organ Injury from E. coli O78 | Beneficial | Large |
| Lactobacillus salivarius HA-118 | Alleviated Organ Injury from Heat Stress | Beneficial | Large |
| Lactobacillus salivarius HA-118 | Enhanced Immune Response After IBDV Vaccination | Beneficial | Large |
| Lactobacillus salivarius HA-118 | Improved Growth Performance | Beneficial | Large |
| Lactobacillus salivarius HA-118 | Increased Relative Weight of Immune Organs | Beneficial | Moderate |
| Lactobacillus salivarius HA-118 | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Improved Immune Response | Beneficial | Large |
| Lactobacillus salivarius SD-5208 | Increased Relative Weight of Immune Organs | Beneficial | Moderate |
| Lactobacillus salivarius SD-5208 | Reduced Organ Injury from Escherichia coli | Beneficial | Large |
| Lactobacillus salivarius SD-5208 | Reduced Organ Injury from Heat Stress | Beneficial | Large |
| Lactobacillus salivarius SD-5851 | Improved Growth Performance | Beneficial | Large |
| Lactobacillus salivarius SD-5851 | Improved Immune Response | Beneficial | Large |
| Lactobacillus salivarius SD-5851 | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius SD-5851 | Reduced Organ Injury | Beneficial | Large |
| Lactobacillus salivarius UALb-07 | Alleviated Organ Injury from Heat Stress | Beneficial | Large |
| Lactobacillus salivarius UALb-07 | Improved Growth Performance | Beneficial | Large |
| Lactobacillus salivarius UALb-07 | Improved Immune Response | Beneficial | Large |
| Lactobacillus salivarius UALb-07 | Increased Relative Weight of Immune Organs | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius UALb-07 | Reduced Organ Injury from Escherichia coli | Beneficial | Large |
| Lactobacillus salivarius UALs07 | Alleviated Organ Injury | Beneficial | Large |
| Lactobacillus salivarius UALs07 | Improved Growth Performance | Beneficial | Large |
| Lactobacillus salivarius UALs07 | Improved Immune Response | Beneficial | Large |
| Lactobacillus salivarius UALs07 | Increased Organ Weights | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Enhanced Immune Response to Vaccine for Infectious Bursal Disease Virus (IBDV) | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Improved Immune Organ Development | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Reduced Odor-Causing Compound Concentrations | Beneficial | Moderate |
| Lactobacillus salivarius UALs07 UAS | Reduced Organ Injury from Escherichia coli | Beneficial | Large |
| Lactobacillus salivarius UALs07 UAS | Reduced Organ Injury from Heat Stress | Beneficial | Large |
| Lactobacillus salivarius VPro 15 | Enhanced Immune Response Following IBDV Vaccination | Beneficial | Large |
| Lactobacillus salivarius VPro 15 | Increased Relative Weight of Immune Organs | Beneficial | Moderate |