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BACILLUS CLAUSII SEPTICEMIA IN A PEDIATRIC PATIENT AFTER TREATMENT WITH PROBIOTICS.

  • 2019-09
  • Pediatric Infectious Disease Journal 38(9)
    • S. Joshi
    • S. Udani
    • Supratim Sen
    • S. Kirolikar
    • A. Shetty

Abstract

Isolated cases of septicemia associated with probiotics have been reported. We describe Bacillus clausii septicemia in a 4-month-old male infant with congenital heart disease following treatment for diarrhea with a probiotic containing B. clausii spores. The septicemia proved refractory to treatment with antibiotics active against the pathogen and progressed to multidrug-resistant sepsis with multiorgan failure.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Bacillus clausiiMultiorgan FailureHarmful
Large
Bacillus clausiiSepticemia IncidenceHarmful
Large
Bacillus clausii MTCC 5980Multiorgan FailureHarmful
Large
Bacillus clausii MTCC 5980Septicemia IncidenceHarmful
Large
Bacillus clausii SC-109Presence of Multidrug-Resistant SepsisHarmful
Large
Bacillus clausii SC-109Septicemia IncidenceHarmful
Large
Bacillus clausii SNZ-1971Septicemia IncidenceHarmful
Large
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