Skip to main content

Abstract

The study reports the effects of Bacillus subtilis 29784 on broiler performance. A total of 1,600 one-day-old Cobb 500 male broiler chicks received either a control diet or the same diet to which B. subtilis 29784 spores were added (1E8 CFU/kg of feed). The birds were slaughtered at 42 D of age. Ileal and cecal tissues and content were collected for histomorphological analysis and 16S rRNA gene sequencing, respectively. The inclusion of B. subtilis 29784 led to an increase of final body weight gain of broilers (+5.7%; P < 0.0001) and an improvement in feed conversion ratio (-5.4%; P < 0.0001). Higher feed efficiency in the Bacillus-fed group was correlated with a significant increase in intestinal microvilli length (+18% in ileum and +17% in cecum; P < 0.001). Among the differences revealed by 16S rRNA analysis, Ruminococcus, Lachnoclostridium, and Anaerostipes were found in higher relative abundance in Bacillus-treated birds at the cecal level. These bacterial genera include species that produce butyrate, the main source of energy for enterocytes and known to be an immune modulator. There was also a slight increase in the Butyrivibrio genus in the cecum, which is known to be an important player in the production of conjugated linoleic acid, also considered an anti-inflammatory compound. In conclusion, dietary supplementation of B. subtilis 29784 significantly improved the growth performance of broilers, likely through beneficial effects on microbiota and host.

Keywords: Bacillus subtilis; broiler; butyrate; gut health; microbiota.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Bacillus SubtilisImproved Feed Conversion RatioBeneficial
Large
Bacillus SubtilisIncreased Body WeightBeneficial
Large
Bacillus SubtilisIncreased Butyrate-Producing Gut BacteriaBeneficial
Moderate
Bacillus SubtilisIncreased Gut Microvilli LengthBeneficial
Large
Bacillus subtilis AB22Improved Feed Conversion RatioBeneficial
Large
Bacillus subtilis AB22Increased Body WeightBeneficial
Large
Bacillus subtilis AB22Increased Butyrate LevelsBeneficial
Moderate
Bacillus subtilis AB22Increased Butyrivibrio Bacteria AbundanceBeneficial
Small
Bacillus subtilis AB22Increased Intestinal Microvilli LengthBeneficial
Large
Bacillus subtilis DE11Improved Feed Conversion RatioBeneficial
Large
Bacillus subtilis DE11Improved Growth PerformanceBeneficial
Large
Bacillus subtilis DE11Increased Butyrate-Producing Gut BacteriaBeneficial
Moderate
Bacillus subtilis DE11Increased Intestinal Microvilli LengthBeneficial
Large
Bacillus subtilis DE111Improved Growth PerformanceBeneficial
Large
Bacillus subtilis DE111Improved Intestinal MorphologyBeneficial
Large
Bacillus subtilis DE111Increased Anti-Inflammatory LevelsBeneficial
Small
Bacillus subtilis DE111Increased Butyrate-Producing Gut BacteriaBeneficial
Moderate
Bacillus subtilis HU58Improved Growth PerformanceBeneficial
Large
Bacillus subtilis HU58Improved Intestinal MorphologyBeneficial
Large
Bacillus subtilis HU58Increased Butyrate-Producing Gut BacteriaBeneficial
Moderate
Bacillus subtilis HU58Increased Conjugated Linoleic Acid LevelsBeneficial
Small
Bacillus subtilis MB40Improved Body WeightBeneficial
Large
Bacillus subtilis MB40Improved Feed Conversion RatioBeneficial
Large
Bacillus subtilis MB40Increased Butyrate-Producing Gut BacteriaBeneficial
Moderate
Bacillus subtilis MB40Increased Conjugated Linoleic Acid ProductionBeneficial
Small
Bacillus subtilis MB40Increased Intestinal Microvilli LengthBeneficial
Large
Bacillus subtilis SNZ-1972Enhanced Immune FunctionBeneficial
Moderate
Bacillus subtilis SNZ-1972Improved Gastrointestinal HealthBeneficial
Large
Bacillus subtilis SNZ-1972Improved Growth PerformanceBeneficial
Large
Bacillus subtilis SNZ-1972Increased Butyrate LevelsBeneficial
Moderate
Bacillus subtilis SNZ-1972Increased Conjugated Linoleic Acid LevelsBeneficial
Small

Pillser helps you make informed health decisions by providing comprehensive, unbiased information about supplements. This includes detailed research on supplement ingredients, their benefits, potential risks, and their overall efficacy. You can contribute by sharing your feedback and suggestions.

Send us an email at support@pillser.com.