Bifidobacterium longum bacteremia in preterm infants receiving probiotics.

2014-12-03
Clinical Infectious Diseases 60(6)
- C. Bertelli
- T. Pillonel
- Anaïs Torregrossa
- G. Prod'Hom
- C. Fischer
- Gilbert GREUB
- E. Giannoni

PubMed: 25472946
DOI: 10.1093/cid/ciu946

Study Design

Type: Case Report
Sample size: n = 2
Population: Premature newborns
Methods: Case report

Highly Cited

Abstract

Administration of probiotics to premature newborns has been shown to prevent necrotizing enterocolitis and reduce all-cause mortality. In our hospital, we documented 2 cases of Bifidobacterium longum subspecies infantis bacteremia in newborns receiving probiotics. By comparative genomics, we confirmed that the strains isolated from each patient originated from the probiotics.

Keywords: Bifidobacterium; genome sequence; newborn; probiotics; sepsis.

Research Insights

Bifidobacterium infantis VPro 53→Bifidobacterium longum infantis Bacteremia
In our hospital, we documented 2 cases of Bifidobacterium longum subspecies infantis bacteremia in newborns receiving probiotics.
Effect
Harmful
Effect size
Moderate
Bifidobacterium infantis VPro 53→Prevention of Necrotising Enterocolitis
Administration of probiotics to premature newborns has been shown to prevent necrotizing enterocolitis and reduce all-cause mortality.
Effect
Beneficial
Effect size
Moderate
Bifidobacterium infantis VPro 53→Reduced All-Cause Mortality
Administration of probiotics to premature newborns has been shown to prevent necrotizing enterocolitis and reduce all-cause mortality.
Effect
Beneficial
Effect size
Moderate