Bifidobacterium longum bacteremia in preterm infants receiving probiotics.
- 2014-12-03
- Clinical Infectious Diseases 60(6)
- C. Bertelli
- T. Pillonel
- Anaïs Torregrossa
- G. Prod'Hom
- C. Fischer
- Gilbert GREUB
- E. Giannoni
- PubMed: 25472946
- DOI: 10.1093/cid/ciu946
Abstract
Administration of probiotics to premature newborns has been shown to prevent necrotizing enterocolitis and reduce all-cause mortality. In our hospital, we documented 2 cases of Bifidobacterium longum subspecies infantis bacteremia in newborns receiving probiotics. By comparative genomics, we confirmed that the strains isolated from each patient originated from the probiotics.
Keywords: Bifidobacterium; genome sequence; newborn; probiotics; sepsis.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Bifidobacterium infantis | Sepsis Management Improvement | Harmful | Large |
| Bifidobacterium infantis BI02 | Reduced Bacteremia Incidence | Harmful | Moderate |
| Bifidobacterium infantis VPro 53 | Bifidobacterium longum infantis Bacteremia | Harmful | Moderate |
| Bifidobacterium infantis VPro 53 | Prevention of Necrotising Enterocolitis | Beneficial | Moderate |
| Bifidobacterium infantis VPro 53 | Reduced All-Cause Mortality | Beneficial | Moderate |
| Bifidobacterium longum subsp. infantis | Reduced Bacteremia in Preterm Infants | Harmful | Moderate |