Biomimetic cyclization of geraniol derivatives, a useful tool in the total synthesis of bioactive monocyclic terpenoids.
- 2011-04-01
- Natural product communications 6(4)
- Valentina Merlini
- Marco Luparia
- Alessio Porta
- Giuseppe Zanoni
- Giovanni Vidari
- PubMed: 21560759
- DOI: 10.1177/1934578x1100600407
Study Design
- Type
- Review
This review is a detailed account of authors' work in the field of biomimetic cyclization of geraniol-like dienes. The very high regio- and enantioselectivity achieved made these elegant reactions a viable tool for the synthesis of monocyclic building blocks used in the synthesis of valued terpenoids, like the precious aroma and perfume constituents' ionones and irones.