Skip to main content

Abstract

This double-blind, randomized clinical trial aimed to evaluate the efficacy and safety of Bifidobacterium breve B-3 (BB-3) for reducing body fat. Healthy individuals were randomized into the BB-3 or placebo group (1:1). Dual-energy X-ray absorptiometry was used to evaluate body fat reduction objectively. In the BB-3 group, body weight was lower than before BB-3 ingestion. Regarding waist circumference, hip circumference, and waist/hip circumference ratio, waist circumference and hip circumference were lower in the BB-3 group than in the placebo group at 12 weeks; the waist/hip circumference ratio was found to decrease at each visit in the BB-3 group, although there was no significant difference in the amount of change after 12 weeks. BB-3 did not cause any severe adverse reactions. Body fat was significantly lower in the BB-3 group than in the placebo group. In conclusion, ingesting BB-3 significantly reduces body weight, waist circumference, and hip circumference. Thus, BB-3 is safe and effective for reducing body fat.

Keywords: Bifidobacterium breve B-3; nutritional supplement; obesity; placebo-controlled study; randomized trial.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Bifidobacterium breveReduced Body FatBeneficial
Large
Bifidobacterium breveReduced Body WeightBeneficial
Moderate
Bifidobacterium breveReduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breveReduced Waist CircumferenceBeneficial
Moderate
Bifidobacterium breveReduced Waist-to-Hip RatioBeneficial
Small
Bifidobacterium breve Bb-03Reduced Body FatBeneficial
Large
Bifidobacterium breve Bb-03Reduced Body WeightBeneficial
Moderate
Bifidobacterium breve Bb-03Reduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breve Bb-03Reduced Waist CircumferenceBeneficial
Moderate
Bifidobacterium breve Bb-03Reduced Waist-to-Hip RatioBeneficial
Small
Bifidobacterium breve Bb-18Reduced Body FatBeneficial
Large
Bifidobacterium breve Bb-18Reduced Body WeightBeneficial
Moderate
Bifidobacterium breve Bb-18Reduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breve Bb-18Reduced Waist CircumferenceBeneficial
Moderate
Bifidobacterium breve Bb-18Reduced Waist-to-Hip RatioBeneficial
Small
Bifidobacterium breve BBr60Absence of Severe Adverse ReactionsNeutral
Small
Bifidobacterium breve Bbr8Reduced Body FatBeneficial
Large
Bifidobacterium breve Bbr8Reduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breve Bbr8Reduced Waist CircumferenceBeneficial
Moderate
Bifidobacterium breve BR03Reduced Body FatBeneficial
Large
Bifidobacterium breve BR03Reduced Body WeightBeneficial
Moderate
Bifidobacterium breve BR03Reduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breve BR03Reduced Waist CircumferenceBeneficial
Moderate
Bifidobacterium breve BR-03Reduced Body FatBeneficial
Large
Bifidobacterium breve BR-03Reduced Body WeightBeneficial
Moderate
Bifidobacterium breve BR-03Reduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breve BR-03Reduced Waist CircumferenceBeneficial
Moderate
Bifidobacterium breve MAK40B22BReduced Body FatBeneficial
Large
Bifidobacterium breve MAK40B22BReduced Body WeightBeneficial
Moderate
Bifidobacterium breve MAK40B22BReduced Hip CircumferenceBeneficial
Moderate
Bifidobacterium breve MAK40B22BReduced Waist CircumferenceBeneficial
Moderate

Pillser helps you make informed health decisions by providing comprehensive, unbiased information about supplements. This includes detailed research on supplement ingredients, their benefits, potential risks, and their overall efficacy. You can contribute by sharing your feedback and suggestions.

Send us an email at support@pillser.com.