Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Clinical Assessment of the Efficacy of Natural Nutraceuticals in Gingival Massage Therapy: A Randomized Clinical Study.

  • 2025-12-10
  • International journal of dental hygiene 24(2)
    • Fizza Khalid
    • Shahbaz Ahmed
    • Waqas Ahmed Farooqui
    • Haseeb Pervaiz
    • Sania Riaz
    • Sumaiya Shabbir
    • Mehwish Ghazal
    • Ziaur Rahman Khan

Study Design

Type
Randomized Controlled Trial (RCT)
Population
participants with gingivitis
Methods
randomised clinical trial (RCT), scaling and root debridement, gingival massage with Aloe vera gel or Sidr honey versus SRD only
Duration
30 days
Funding
Unclear

Objective

The purpose of this randomized clinical trial was to assess the efficacy of gingival massage therapy with Aloe vera gel and sidr honey and to find out the difference in their efficacies, in reducing clinical parameters in gingival inflammation.

Method

Participants with gingivitis were selected in this randomised clinical trial (RCT). Scaling and root debridement (SRD) was performed and baseline plaque index (PI), gingival index (GI) and bleeding on probing (BOP) were recorded and participants were randomly allocated into three groups. Group A: SRD and gingival massage (GM) with Aloe vera gel, Group B: SRD and GM with Sidr honey and Group C: SRD only. On the 30th day all clinical parameters were re-evaluated.

Results

Gingival massage therapy with both interventions showed improvement in all clinical parameters, when used as an adjunct to non-surgical periodontal therapy. Aloe vera versus control showed improvements in PI (-0.57) and GI (-0.32); honey versus control in PI (-0.68) and GI (-0.63) and Aloe vera versus honey in PI (0.11) and GI (-0.57). BOP was also reduced in all three groups.

Conclusion

This ClinicalTrial showed that gingival massage therapy with Aloe vera gel and sidr honey was effective in reducing plaque index, gingival index and bleeding on probing when used as adjuncts in patients with gingivitis. However, group B was more effective when compared with group A and group C. Future RCTs will further evaluate the synergistic effects of these adjuncts in periodontal treatments.

Trial registration

ClinicalTrials.gov identifier: NCT05231096.

Research Insights

  • Aloe→Reduced Bleeding on Probing (BOP)

    gingival massage therapy with Aloe vera gel and sidr honey was effective in reducing plaque index, gingival index and bleeding on probing

    Effect
    Beneficial
    Effect size
    Small
  • Aloe→Reduced Gingival Index

    Aloe vera versus control showed improvements in PI (-0.57) and GI (-0.32); honey versus control in PI (-0.68) and GI (-0.63) and Aloe vera versus honey in PI (0.11) and GI (-0.57). BOP was also reduced in all three groups.

    Effect
    Beneficial
    Effect size
    Moderate
  • Aloe→Reduced Plaque Index

    Aloe vera versus control showed improvements in PI (-0.57) and GI (-0.32); honey versus control in PI (-0.68) and GI (-0.63) and Aloe vera versus honey in PI (0.11) and GI (-0.57). BOP was also reduced in all three groups.

    Effect
    Beneficial
    Effect size
    Moderate
Back to top