- 2025-12-23
- Journal of pain research 18
- Peng Zhang
- Ying Zhao
- Hailing Mu
- Jin Zhang
- Fan Zhang
- Shaolin Wang
Study Design
- Type
- Clinical Trial
- Sample size
- n = 59
- Population
- 59 patients
- Methods
- randomized trial; Group L (n = 30): Intravenous lidocaine (bolus 1.5 mg/kg followed by 25 μg/kg/min infusion); Group T (n = 29): Bilateral ultrasound-guided TFP block with 40 mL of 0.33% ropivacaine; Both groups underwent standardized general anesthesia and patient-controlled intravenous analgesia (PCIA)
Objective
To compare the effects of transversalis fascia plane (TFP) block versus intravenous lidocaine infusion on early recovery after gynecologic laparoscopic surgery.Methods
In this randomized trial, 59 patients were assigned to: Group L (n = 30): Intravenous lidocaine (bolus 1.5 mg/kg followed by 25 μg/kg/min infusion); Group T (n = 29): Bilateral ultrasound-guided TFP block with 40 mL of 0.33% ropivacaine. Both groups underwent standardized general anesthesia and patient-controlled intravenous analgesia (PCIA). The primary outcome was quality of recovery-15 (QoR-15) scores on postoperative day 1 (POD1). Secondary outcomes included numerical rating scale (NRS), PCIA demand, inflammatory markers (IL-6, TNF-α), time to first flatus, and adverse events.Results
No significant differences were observed in QoR-15 scores, intraoperative drug consumption, pain scores, PCIA demand, inflammatory markers, or adverse events (P > 0.05). However, Group L exhibited a shorter time to first flatus (P < 0.05).Conclusion
TFP block and lidocaine infusion provided comparable recovery quality, though lidocaine may accelerate gastrointestinal recovery.