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Comparison of the Probiotic Potential between Lactiplantibacillus plantarum Isolated from Kimchi and Standard Probiotic Strains Isolated from Different Sources

  • 2021-09-08
  • Foods 10(9)
    • C. Jeong
    • Hyejin Sohn
    • Hyelyeon Hwang
    • Ho-Jae Lee
    • Tae-Woon Kim
    • Dong-Sub Kim
    • Chun-Sung Kim
    • S. Han
    • S. Hong

Abstract

In the present study, the properties of the Lactiplantibacillus (Lpb.) plantarum WiKim0112 isolated from kimchi were evaluated by comparing its probiotic properties to those of Lpb. plantarum WCFS1 and KACC 11451 isolated from different sources. In both pH 2 and 3, media containing pepsin, Wikim0112, and WCFS1 showed higher cell viability than KACC11451. Viability of all Lpb. plantarum strains in a medium containing pancreatin and bile salt oxgall was significantly decreased compared to the control. WCFS1 showed the highest thermotolerance, followed by Wikim0112 and KACC11451. Wikim0112 showed a similar level of antibacterial activity to WCFS1 and exhibited an overall higher antibacterial activity than KACC11451 against six pathogens. All Lpb. plantatum strains showed high antioxidant activities in SOD, DPPH, and ABTS assays, especially Wikim0112 and WCFS1 exhibited a higher antioxidant activity than KACC11451. All Lpb. plantarum strains showed approximately 60-62% adhesion rates to Caco-2 cells. Moreover, in LPS-stimulated Caco-2 cells, all Lpb. plantarum strains significantly decreased the mRNA expression of pro-inflammatory cytokines (i.e., IL-1β, IL-6, and TNF-α); Wikim0112 significantly increased the mRNA expression of IL-4 and IFN-γ. Wikim0112 was resistant to streptomycin and vancomycin, whereas WCFS1 and KACC11451 were resistant to four (clindamycin, ciprofloxacin, tetracycline, and vancomycin) and three (ciprofloxacin, tetracycline, and vancomycin) antibiotics, respectively. These results, taken together, indicated that compared to Lpb. plantarum strains isolated from different sources, Wikim0112 showed desirable probiotic properties, suggesting its potential applications in the food and pharmaceutical industries.

Keywords: Lactiplantibacillus plantarum; anti-inflammatory activity; kimchi; probiotic properties.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactiplantibacillus plantarum LP-01Adhesion to Caco-2 CellsNeutral
Small
Lactiplantibacillus plantarum LP-01Improved Cell ViabilityBeneficial
Moderate
Lactiplantibacillus plantarum LP-01Improved ThermotoleranceBeneficial
Moderate
Lactiplantibacillus plantarum LP-01Increased Antibacterial ActivityBeneficial
Large
Lactiplantibacillus plantarum LP-01Increased Anti-Inflammatory Cytokine LevelsBeneficial
Moderate
Lactiplantibacillus plantarum LP-01Increased Antioxidant ActivityBeneficial
Moderate
Lactiplantibacillus plantarum LP-01Reduced Pro-Inflammatory CytokinesBeneficial
Moderate
Lactiplantibacillus plantarum LP-1Improved Antibacterial ActivityBeneficial
Large
Lactiplantibacillus plantarum LP-1Improved Cell ViabilityBeneficial
Moderate
Lactiplantibacillus plantarum LP-1Increased Antioxidant ActivityBeneficial
Moderate
Lactiplantibacillus plantarum LP-1Increased Intestinal Cell AdhesionBeneficial
Moderate
Lactiplantibacillus plantarum LP-1Reduced Inflammation LevelsBeneficial
Moderate

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