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Abstract

Bifidobacterium animalis subsp. lactis BB-12 is a commercially available probiotic strain used throughout the world in a variety of functional foods and dietary supplements. The benefits of BB-12 have been documented in a number of independent clinical trials. Determination of the complete genome sequence reveals a single circular chromosome of 1,942,198 bp with 1,642 predicted protein-encoding genes, 4 rRNA operons, and 52 tRNA genes. Knowledge of this sequence will lead to insight into the specific features which give this strain its probiotic properties.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Bifidobacterium animalisImproved General HealthBeneficial
Moderate
Bifidobacterium animalis subsp. lactisImproved Gut MicrobiotaBeneficial
Large

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