Complete Genome Sequence of Bifidobacterium animalis subsp. lactis BB-12, a Widely Consumed Probiotic Strain
- 2010-05
- Journal of Bacteriology 192(9)
- C. Garrigues
- E. Johansen
- M. Pedersen
- PubMed: 20190051
- DOI: 10.1128/JB.00109-10
Abstract
Bifidobacterium animalis subsp. lactis BB-12 is a commercially available probiotic strain used throughout the world in a variety of functional foods and dietary supplements. The benefits of BB-12 have been documented in a number of independent clinical trials. Determination of the complete genome sequence reveals a single circular chromosome of 1,942,198 bp with 1,642 predicted protein-encoding genes, 4 rRNA operons, and 52 tRNA genes. Knowledge of this sequence will lead to insight into the specific features which give this strain its probiotic properties.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Bifidobacterium animalis | Improved General Health | Beneficial | Moderate |
| Bifidobacterium animalis subsp. lactis | Improved Gut Microbiota | Beneficial | Large |