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Complete genome sequence of Lactobacillus helveticus H9, a probiotic strain originated from kurut.

  • 2015-01
  • Journal of Biotechnology 194
    • Yongfu Chen
    • Wenyi Zhang
    • Zhihong Sun
    • Bilighe Meng
    • Heping Zhang


Lactobacillus helveticus H9 is a probiotic strain that is able to produce antihypertensive peptides during milk fermentation. Its genome has a circular 1.87Mb chromosome. Comparative genomic analysis revealed that the component of proteinases, peptide transport systems and peptidases in L. helveticus appeared to be strain-specific. Such information may help us to understand how the proteolytic system is related to its probiotic properties.

Keywords: Antihypertensive peptides; Lactobacillus helveticus; Proteolytic system.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Lactobacillus helveticusReduced Blood PressureBeneficial
Lactobacillus helveticus R0052Increased Antihypertensive Peptide ProductionBeneficial
Lactobacillus helveticus Rosell-52Reduced Blood PressureBeneficial
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