Complete genome sequence of Lactobacillus helveticus H9, a probiotic strain originated from kurut.
- 2015-01
- Journal of Biotechnology 194
- Yongfu Chen
- Wenyi Zhang
- Zhihong Sun
- Bilighe Meng
- Heping Zhang
- PubMed: 25499075
- DOI: 10.1016/j.jbiotec.2014.11.038
Abstract
Lactobacillus helveticus H9 is a probiotic strain that is able to produce antihypertensive peptides during milk fermentation. Its genome has a circular 1.87Mb chromosome. Comparative genomic analysis revealed that the component of proteinases, peptide transport systems and peptidases in L. helveticus appeared to be strain-specific. Such information may help us to understand how the proteolytic system is related to its probiotic properties.
Keywords: Antihypertensive peptides; Lactobacillus helveticus; Proteolytic system.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Lactobacillus helveticus | Reduced Blood Pressure | Beneficial | Moderate |
| Lactobacillus helveticus R0052 | Increased Antihypertensive Peptide Production | Beneficial | Moderate |
| Lactobacillus helveticus Rosell-52 | Reduced Blood Pressure | Beneficial | Moderate |