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Abstract

We report the genome sequence of Bifidobacterium animalis subspecies lactis BL3, which has preventive properties on acute colitis and colon cancer. The genome of BL3, which was isolated from Korean faeces, consisted of a 1 944 323 bp size single chromosome, and its G+C content was 60.5%. Genome comparison against the closest Bifidobacterium animalis strain revealed that BL3 had particularly different regions of four areas encoding flavin-nucleotide-binding protein, transposase, multidrug ABC transporter and ATP binding protein.

Keywords: Bifidobacterium; IBD; PacBio; genome sequence; probiotics.

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Bifidobacterium animalis subsp. lactis BLC1Reduced Incidence of Acute ColitisBeneficial
Moderate
Bifidobacterium animalis subsp. lactis BLC1Reduced Incidence of Colon CancerBeneficial
Moderate
Bifidobacterium lactis BL818Reduced Colon Cancer RiskBeneficial
Large
Bifidobacterium lactis BL818Reduced Severity of Acute ColitisBeneficial
Large
Bifidobacterium lactis BLC-1Reduced Incidence of Acute ColitisBeneficial
Moderate
Bifidobacterium lactis BLC-1Reduced Incidence of Colon CancerBeneficial
Moderate

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