Complete Genome Sequences of Probiotic Strains Bifidobacterium animalis subsp. lactis B420 and Bi-07
- 2012-08
- Journal of Bacteriology 194(15)
- Buffy Stahl
- R. Barrangou
- PubMed: 22815448
- DOI: 10.1128/JB.00766-12
Study Design
- Methods
- Comparative genomic analysis.
Abstract
We present the complete genomes of Bifidobacterium animalis subsp. lactis B420 and Bi-07. Comparative genomic analysis with the type strain DSMZ10140 revealed 40 to 55 single nucleotide polymorphisms (SNPs) and an indel in a clustered regularly interspaced short palindromic repeat (CRISPR) locus. These genetic differences provide a molecular basis for strain typing within the two main phylogenetic groups of this monomorphic species.