Diet, oxidative stress and MAFLD: a mini review.
- 2025-03-04
- Frontiers in nutrition 12
- Zenan Hu
- Hanxun Yue
- Na Jiang
- Liang Qiao
- PubMed: 40104813
- DOI: 10.3389/fnut.2025.1539578
Study Design
- Type
- Review
Globally, metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), is a common chronic liver disease. The progression of MAFLD leads to a vicious cycle in which oxidative stress results from the disease that is augmenting de-novo lipid levels and increases steatosis. Most non-enzymatic antioxidants are present in food. Therefore, the present review summarizes the findings of studies on food-derived antioxidants and presents an oxidative stress-related regulatory network in MAFLD, offering new ideas for MAFLD prevention and treatment.