Different effects of probiotic species/strains on infections in preschool children: A double-blind, randomized, controlled study.
- 2009-02
- Vaccine 27(7)
- PubMed: 19114073
- DOI: 10.1016/j.vaccine.2008.11.114
Study Design
- Type
- Randomized Controlled Trial (RCT)
- Sample size
- n = 1,062
- Population
- Children under age 5
- Methods
- Randomized Controlled Trial
- Large Human Trial
- Highly Cited
Abstract
Treatment and prevention of pediatric infectious diseases of three commercial probiotic products were evaluated by a double-blind, randomized, controlled trial. Test subjects under age 5, 1062 in total, were distributed randomly into four groups. This investigation showed that L. casei rhamnosus can control bacterial, viral and respiratory infections; a multi-species probiotic reduced gastrointestinal disease significantly. Long-term consumption of L. rhamnosus T cell-1 decreased the incidence of bacterial infection.
Research Insights
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