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Study Design

Type
Randomized Controlled Trial (RCT)
Population
53 healthy females aged 19-33
Methods
Randomized, single-blind, placebo-control design; 6-week supplementation with Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 or placebo; anthropometric measures pre and post-treatment.

Purpose

Probiotic supplements are gaining popularity worldwide. This trend is especially present in females, and a common motivation for consumption is weight loss, no matter the BMI. The aim of this study was to investigate the effects of probiotic supplementation on weight loss in healthy, young adult females and to put claims made by manufacturers of such products to the test.

Methods

The study utilizes a randomized, single-blind, placebo-control design. 53 females aged 19-33 were enrolled, and 38 completed the trial. A 6 week supplementation with Bifidobacterium lactis BS01 and Lactobacillus acidophilus LA02 or placebo was conducted. Anthropometric measures (body mass, BMI, body fat percentage, arm skinfold fat, waist circumference, and WHR) were applied pre and post-treatment.

Results

No significant changes in anthropometric measures were observed in both supplementation and placebo groups.

Conclusion

The results of this investigation do not support claims made by probiotic products manufacturers, that they aid weight loss. Our results seem to support an argument that weight loss is mostly associated with food habits and dietary behaviors, not probiotic intake. It is possible that probiotic supplementation may play a facilitating weight loss but has no effect without dietary intervention. Another possible explanation is that due to strain specificity-bacteria strains used in this study are not effective for weight loss.

Level of evidence

I: randomized controlled trial.

Research Insights

SupplementDoseHealth OutcomeEffect TypeEffect SizeSource
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