Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Effect of green tea supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials.

  • 2025-06-12
  • Blood pressure 34(1)
    • Mahshid Rezaei
    • Neda Akhavan
    • Fereshteh Fathi
    • Seyyed Mohammad Alavi
    • Mahdiyeh Fadaii
    • Mohammad Jafar Dehzad
    • Moein Askarpour

Study Design

Type
Meta-Analysis
Sample size
n = 36
Population
adults (≥18 years)
Methods
meta-analysis of randomised controlled trials; PubMed, Scopus, and Web of Science searched through January 2024; weighted mean differences pooled using random-effects models

Background

Hypertension (HTN) is a leading contributor to cardiovascular disease (CVD). Green tea has been proposed as a natural intervention for blood pressure (BP) management due to its antioxidant content. This study aimed to systematically evaluate the effect of green tea supplementation on systolic (SBP) and diastolic blood pressure (DBP) using a meta-analysis of randomised controlled trials (RCTs).

Methods

Eligibility criteria were defined using the PICOS framework. PubMed, Scopus, and Web of Science were searched through January 2024 for randomised controlled trials in adults (≥18 years) comparing green tea supplementation with control or placebo, reporting pre- and post-intervention systolic and diastolic blood pressure (SBP and DBP). Weighted mean differences (WMDs) and 95% confidence intervals (CIs) were pooled using random-effects models. Subgroup analyses and dose-response analyses were performed.

Results

A total of 36 RCTs were included. Green tea reduced SBP (WMD: -1.08 mmHg; 95% CI: -1.98, -0.18; I2 = 85.0%) and DBP (WMD: -1.09 mmHg; 95% CI: -1.67, -0.50; I2 = 74.0%). Subgroup analyses showed stronger effects in participants with elevated baseline BP (SBP ≥120 mmHg), those consuming <500 mg/day green tea, studies ≤8 weeks, Asian populations, and women. No clear association was found between BP changes and tea dose or intervention duration.

Conclusion

Green tea supplementation is associated with modest reductions in SBP and DBP. Given the heterogeneity and lack of clear dose-duration effects, green tea is better considered a complementary approach for managing blood pressure.

Research Insights

  • green tea→Reduced Diastolic Blood Pressure

    Green tea reduced DBP (WMD: -1.09 mmHg; 95% CI: -1.67, -0.50; I² = 74.0%)

    Effect
    Beneficial
    Effect size
    Small
    Dose
    ranging across included studies, subgroup analysis used <500 mg/day vs ≥500 mg/day
  • green tea→Reduced Systolic Blood Pressure

    Green tea reduced SBP (WMD: -1.08 mmHg; 95% CI: -1.98, -0.18; I² = 85.0%)

    Effect
    Beneficial
    Effect size
    Small
    Dose
    ranging across included studies, subgroup analysis used <500 mg/day vs ≥500 mg/day
Back to top