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The objective of this study was to investigate the effect of pediocin A in in vitro caecal fermentations. Pediococcus pentosaceus FBB61, pediocin A producer (bac+) and its isogenic mutant (bac-) Ped. pentosaceus FBB61-2 were added to fermentation vessels. Pediocin A did not alter the normal activity of caecal microflora. Nevertheless, the presence of pediocin A producer strain reduced proteolysis compared to the mutant strain as indicated by ammonia concentrations (P < 0.05), and isobutyric and isovaleric molar proportions (P < 0.05).

Research Insights

SupplementHealth OutcomeEffect TypeEffect Size
Pediococcus pentosaceus KABP™-041Reduced ProteolysisBeneficial
Pediococcus pentosaceus PP06Reduced ProteolysisBeneficial

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