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Effects of Capsicum annuum supplementation on the components of metabolic syndrome: a systematic review and meta-analysis.

  • 2020-12-01
  • Scientific reports 10(1)
    • Hwan-Hee Jang
    • Jounghee Lee
    • Sung-Hyen Lee
    • Young-Min Lee

Study Design

Type
Meta-Analysis
Sample size
n = 609
Population
11 studies (n = 609)
Methods
Systematic review and meta-analysis of randomized controlled trials; searched PubMed, Embase, Google Scholar, Cochrane Library searched up to April 2020; random-effects model
  • Rigorous Journal
Metabolic syndrome (MetS) has increasingly gained importance as the main risk factor for cardiovascular diseases and type II diabetes mellitus. Various natural compounds derived from plants are associated with beneficial effects on the incidence and progression of MetS. This study aimed to evaluate the effects of Capsicum annuum on factors related to MetS by assessing randomized controlled trials (written in English). We searched the online databases of PubMed, Embase, Google scholar, and Cochrane Library up to April 2020. 'Patient/Population, Intervention, Comparison and Outcomes' format was used to determine whether intervention with C. annuum supplementation compared with placebo supplementation had any effect on the components of MetS among participants. We considered standardized mean differences (SMD) with 95% confidence intervals (CI) as effect size measures using random-effects model. Analysis of the included 11 studies (n = 609) showed that C. annuum supplementation had significant effect on low density lipoprotein-cholesterol [SMD = - 0.39; 95% CI - 0.72, - 0.07; P = 0.02; prediction interval, - 1.28 to 0.50] and marginally significant effect on body weight [SMD = - 0.19; 95% CI - 0.40, 0.03; P = 0.09]. However, larger and well-designed clinical trials are needed to investigate the effects of C. annuum on MetS.

Research Insights

  • Chili→Reduced Body Weight

    marginally significant effect on body weight [SMD = - 0.19; 95% CI - 0.40, 0.03; P = 0.09]

    Effect
    Neutral
    Effect size
    Small
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